The American Medical Formulary, authored by John James Reese and first published in 1850, is a seminal work in the field of medical pharmacology. This comprehensive reference book consolidates medical knowledge from both American and British pharmacopoeias, offering a detailed compilation of medicinal formulas, their applications, and associated antidotes. Designed primarily for medical and pharmaceutical students, it serves as a bridge between traditional herbal practices and emerging scientific approaches in medicine.​

Reese’s formulary is meticulously organized, presenting numerous standard formulas derived from reputable American and European authorities. Each entry provides insights into the medical properties and uses of various medicines, including their therapeutic applications and potential toxicities. The inclusion of antidotes and diagnostic tests further enhances its utility as a practical guide for healthcare practitioners. By integrating diverse sources, Reese offers a holistic perspective on medicinal practices of the time, reflecting a blend of empirical knowledge and evolving scientific understanding.​

Beyond its technical content, the formulary embodies a historical snapshot of 19th-century medical practices. It highlights the transition from traditional herbal remedies to more standardized pharmaceutical preparations, marking a significant shift in medical paradigms. The work underscores the importance of empirical research and cross-cultural knowledge exchange in advancing medical science. For contemporary readers, it provides valuable context for understanding the evolution of pharmacology and the foundational principles that continue to influence modern medical practices.​

The American Medical Formulary stands as a testament to the rigorous scientific inquiry and cross-cultural collaboration that have shaped the field of medicine. Its detailed compendium of medicinal formulas, coupled with insights into their properties and uses, offers an indispensable resource for those interested in the historical development of medical and pharmaceutical sciences. Reese’s work not only serves as a practical guide but also as a reflection of the enduring quest for knowledge and improvement in the healing arts.