A Synopsis or Systematic Catalogue of the Medical Plants of the United States, authored by Asahel Clapp and published in 1852, is a comprehensive reference that systematically catalogs the medicinal plants native to the United States. This work reflects the 19th-century emphasis on cataloging and understanding the natural resources available for medicinal use, providing a structured overview of the botanical wealth of the nation.​

The book meticulously organizes information on various plant species, detailing their botanical characteristics, habitats, and known medicinal properties. Clapp’s systematic approach offers readers a clear framework for identifying and understanding the therapeutic uses of these plants. The catalog serves as a valuable resource for practitioners of herbal medicine, pharmacists, and botanists interested in the traditional uses of American flora.​

Clapp’s work is notable for its attempt to bridge the gap between traditional herbal knowledge and the emerging scientific approaches of the time. By documenting the medicinal plants systematically, he provided a foundation for future research and application in medical botany. The catalog not only lists the plants but also includes insights into their preparation and administration, reflecting the practical aspects of herbal medicine during that era.​

A Synopsis or Systematic Catalogue of the Medical Plants of the United States stands as a significant contribution to the field of medical botany. It encapsulates the rich tradition of herbal medicine in the United States and serves as a testament to the importance of preserving and understanding the natural remedies that have been utilized for generations. Clapp’s work remains a valuable reference for those interested in the historical and practical aspects of medicinal plants.