​A Century of American Medicine, 1776–1876 is a seminal work that chronicles the evolution of medical practices in the United States over a hundred years. Published in 1876 and edited by Edward H. Clarke, this volume compiles contributions from prominent medical figures of the era, each addressing a specific facet of American medicine. The book serves as both a historical record and a reflection on the advancements and challenges faced by the medical community during this period.​

The first section, authored by Edward H. Clarke, delves into practical medicine, exploring the prevailing treatments, diagnostic methods, and the overall approach to patient care. Henry Jacob Bigelow’s contribution provides a detailed account of the discovery of modern anesthesia, highlighting its transformative impact on surgical procedures and patient outcomes. Samuel D. Gross offers an in-depth examination of surgery, discussing its development, the introduction of new techniques, and the establishment of surgical education. T. Gaillard Thomas focuses on obstetrics and gynecology, tracing the progression of maternal and child healthcare, and emphasizing the importance of specialized knowledge in these fields. John S. Billings concludes the volume with a discussion on medical literature and institutions, reflecting on the growth of medical education, the establishment of medical societies, and the dissemination of medical knowledge through publications.​

Collectively, these essays provide a comprehensive overview of American medicine in the 19th century, illustrating the shift from rudimentary practices to more scientific and institutionalized approaches. The work underscores the contributions of American physicians to the broader medical community and their role in shaping the future of healthcare. While acknowledging the progress made, the volume also highlights the challenges and limitations of the time, offering valuable insights for contemporary readers interested in the history of medicine.​

A Century of American Medicine is a critical resource for understanding the development of medical practices in the United States. Its detailed accounts and analyses provide a window into the past, allowing readers to appreciate the advancements achieved and the enduring legacy of 19th-century American medicine.