​”Reasons for Adopting the Rational System of Medicine” by Fewster Robert Horner, published in 1857, is a compelling treatise advocating for a shift from traditional homeopathic practices to a more empirical and scientific approach to medicine. Addressed as a letter to the Governors of the Hull General Infirmary, Horner’s work underscores the necessity of grounding medical practice in observation, experimentation, and logical reasoning. He critiques the prevailing reliance on anecdotal evidence and untested remedies, emphasizing the importance of a methodical approach to diagnosis and treatment.​

Horner’s central argument revolves around the need for a medical system that prioritizes patient welfare through evidence-based practices. He highlights the dangers of adhering to outdated methods that lack scientific validation, pointing out that such practices can lead to ineffective or even harmful treatments. By advocating for the rational system, Horner envisions a medical landscape where treatments are subjected to rigorous testing and continuous refinement, ensuring that patient care evolves alongside advancements in medical knowledge.​

The book also delves into the ethical responsibilities of medical practitioners. Horner posits that physicians have a moral obligation to employ treatments that have been proven effective through scientific inquiry. He argues that clinging to traditional methods without scrutiny not only undermines the progress of medicine but also compromises patient trust and safety. By embracing a rational approach, Horner believes that the medical community can foster greater public confidence and deliver more consistent, effective care.​

“Reasons for Adopting the Rational System of Medicine” serves as a seminal work advocating for the modernization of medical practice. Horner’s insights remain relevant, reminding contemporary practitioners of the enduring importance of evidence-based medicine. His call for a systematic, scientific approach to healthcare continues to resonate, underscoring the timeless value of integrating empirical research into medical decision-making.