The New England Botanic Medical and Surgical Journal, Volume 1, published in 1827 by Wells and Lilly, stands as a significant contribution to early American medical literature. Edited by Walter Channing and John Ware, this volume reflects the period’s burgeoning interest in integrating botanical knowledge with medical practice, a hallmark of the eclectic medical movement. The journal aimed to bridge traditional herbal remedies with emerging scientific methodologies, offering a comprehensive view of medical practices of the time.​

This inaugural volume encompasses a diverse array of articles, case studies, and reviews that delve into the therapeutic applications of various plants, surgical techniques, and medical theories. It serves as a platform for physicians and botanists to share their findings and observations, fostering a collaborative environment for advancing medical knowledge. The inclusion of detailed case reports provides insights into the practical challenges and successes faced by practitioners, highlighting the evolving nature of medical treatments and patient care.​

A notable aspect of the journal is its emphasis on the role of botany in medicine. The editors and contributors advocate for the systematic study of plants and their medicinal properties, recognizing the potential of botanical remedies in treating various ailments. This perspective underscores a commitment to exploring natural resources for therapeutic purposes, aligning with the broader movement of medical reform that sought to diversify and enhance treatment options beyond conventional methods.​

Volume 1 of the New England Botanic Medical and Surgical Journal offers a rich tapestry of medical and botanical knowledge reflective of early 19th-century practices. Its contents not only document the medical thinking of the era but also contribute to the historical understanding of the integration of botany into medical science. The journal stands as a testament to the period’s dedication to expanding the horizons of medical treatment through the inclusion of botanical studies.