“Formulary for the Preparation and Mode of Employing Several New Remedies” is a seminal work in the field of pharmacology, originally authored by the esteemed French physiologist François Magendie. This English translation, enriched with an introduction and extensive notes by Charles Thomas Haden and further contributions by Robley Dunglison, was published in London in 1825. The book serves as a comprehensive guide to the preparation and application of a range of novel medicinal substances that were emerging in the early 19th century. It reflects the period’s shift towards a more empirical and scientific approach to medicine, emphasizing the importance of precise dosages and standardized preparations.
The formulary meticulously details the properties, preparation methods, and therapeutic uses of various substances such as morphine, iodine, quinine, cinchonine, hydrocyanic acid, narcotine, strychnine, nux vomica, emetine, atropine, picrotoxine, brucine, and lupuline. Each entry provides insights into the chemical nature of these compounds, their physiological effects, and guidelines for their clinical application. For instance, the inclusion of quinine and cinchonine highlights the growing understanding of their efficacy in treating malaria, while the discussion on morphine underscores its significance as a potent analgesic. The book also addresses the challenges associated with these substances, such as toxicity and the need for careful dosing, reflecting a nuanced understanding of their potential benefits and risks.
An appendix in this edition incorporates advancements from the fourth edition of Magendie’s original work, published in Paris in 1824. This section introduces additional compounds like the hydriodates of potass and soda, ioduret of mercury, cyanurets of potassium and zinc, oil of croton tiglium, piperine, and jalapine. These additions signify the rapid evolution of pharmaceutical knowledge during this era and the ongoing efforts to explore and document new therapeutic agents. The formulary’s systematic approach to cataloging these substances, along with practical instructions for their use, made it an invaluable resource for physicians and pharmacists seeking to incorporate contemporary remedies into their practice.
This formulary stands as a testament to the transformative period in medical history when empirical research and chemical analysis began to profoundly influence therapeutic practices. By providing detailed information on the preparation and administration of new medicinal compounds, it played a crucial role in standardizing treatments and advancing the scientific foundation of medicine. The collaborative efforts of Magendie, Haden, and Dunglison in producing this work underscore the importance of cross-cultural and interdisciplinary contributions to medical progress.