​”An Address: Introductory to Opening the Southern Botanico-Medical College” by A.M. Spalding, published in 1842, is a seminal work that marks the establishment of the Southern Botanico-Medical College. This address serves as a foundational document, outlining the college’s mission to integrate botanical principles into medical education and practice. Spalding emphasizes the importance of herbal medicine, advocating for its inclusion in the medical curriculum as a means to promote holistic and accessible healthcare.​

In his address, Spalding critiques the prevailing medical practices of the time, which often relied heavily on invasive procedures and chemical treatments. He argues for a return to natural remedies, drawing upon the rich traditions of herbal medicine that have been used for centuries. By establishing the Southern Botanico-Medical College, Spalding aims to formalize the study of botanical medicine, providing structured education and training for future practitioners. This approach not only honors traditional healing methods but also seeks to make healthcare more affordable and accessible to the broader population.​

The address also highlights the college’s commitment to scientific rigor and empirical research. Spalding underscores the necessity of studying the physiological effects of plants and conducting clinical trials to validate their efficacy. This emphasis on evidence-based practice reflects a forward-thinking vision, aiming to bridge the gap between traditional herbal knowledge and modern medical science. By doing so, the college positions itself at the forefront of a progressive movement in medical education, one that values both tradition and innovation.​

Spalding’s address touches upon the ethical responsibilities of medical practitioners. He advocates for a compassionate approach to patient care, one that respects the individual’s dignity and autonomy. This perspective aligns with the college’s broader mission to cultivate not only skilled physicians but also morally grounded individuals who are committed to serving their communities. In essence, the address lays the groundwork for a medical institution that seeks to harmonize the wisdom of the past with the advancements of the present, fostering a more humane and effective healthcare system.