​Francis Peyre Porcher’s 1847 work, “A Medico-Botanical Catalogue of the Plants and Ferns of St. John’s, Berkly, South-Carolina,” stands as a testament to the rich interplay between botany and medicine in the 19th century. As an inaugural thesis for the Medical College of the State of South Carolina, Porcher meticulously documented the diverse flora of the St. John’s region, emphasizing their medicinal properties and traditional uses. This catalogue not only reflects the scientific rigor of its time but also offers insights into the local knowledge systems that valued the therapeutic potential of native plants.​

The catalogue systematically lists various plants and ferns, detailing their botanical characteristics alongside their applications in traditional medicine. Porcher’s approach underscores the significance of indigenous knowledge, where local communities relied on these plants for treating ailments and maintaining health. By bridging empirical observations with traditional practices, the work serves as a valuable resource for understanding the historical context of herbal medicine in the American South.​

Porcher’s dedication to preserving this knowledge is evident in his thorough documentation, which includes not only the scientific names and descriptions of the plants but also their habitats and the specific parts used for medicinal purposes. Such detailed records provide a window into the ecological and cultural landscape of the time, highlighting the integral role of plants in daily life and healthcare. This catalogue, therefore, is more than a botanical inventory; it is a cultural artifact that captures the essence of a community’s relationship with its natural environment.​

In today’s context, Porcher’s work remains relevant, offering a foundation for contemporary studies in ethnobotany and the history of medicine. It reminds us of the enduring value of traditional knowledge systems and the importance of preserving such legacies for future generations. By revisiting and studying these historical documents, we can gain a deeper appreciation for the roots of modern herbal medicine and the timeless connection between humans and the plant world.​